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Beilstein J. Org. Chem. 2011, 7, 1562–1569, doi:10.3762/bjoc.7.184
Graphical Abstract
Scheme 1: Compounds studied with the voltage-clamp experiment.
Scheme 2: Synthesis of phthalate compounds.
Figure 1: Channel activities of compound 1. A: Regular “square-top” activity. Conditions: 1 M KCl buffered to...
Figure 2: Channel activities of compound 2. A: Rapid flickering. Conditions: 1 M CsCl, +100 mV; B: Semiregula...
Figure 3: Conversion of a current–time profile of compound 5 (top) into conductance–time profile (bottom) by ...
Figure 4: Single-molecule structure–activity relationships for compounds 1–8. Grids are given in the followin...
Figure 5: Voltage-dependent opening of compound 1. Inset: Exponential dependence of the mean current on the p...